Pedigree analysis problem with solution (Example 19)

Pedigree analysis problem with solution (Example 19)

Q) The trait represented in the following pedigree is expressed only in the males of the family. Is the trait Y linked? Why or why not? If you believe the trait is not Y linked, propose an alternate explanation for its inheritance.

Answer: The trait cannot be Y linked

Reason:

  • Y-linked traits are passed from father to son never from mother to son. Here this criterion is not satisfied.
  • An affected father is having an unaffected son (In Y linked trait all son of affected father must be affected)

This trait cannot be X linked

  • It is often passed from father to son, whereas X-linked traits are passed from father to daughter.

The most probable mode of inheritance for this trait is sex-limited (only in males) autosomal dominant.

 

 

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