Pedigree analysis problem with solution (Example 17)

Pedigree analysis problem with solution (Example 17)

Q) Draw a pedigree that represents an autosomal dominant trait, sex-limited to males, and that excludes the possibility that the trait is Y-linked.

Answer:

Reasons for excluding Y linkage in this pedigree

  • Not all the sons of an affected male are affected.
  • Here unaffected male has affected sons.
  • Females cannot transmit Y linked disease since they don’t have Y chromosome. But this pedigree shows that the trait is through an unaffected female to her sons.

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